Current Literature in Glycobiology / Glyco Journal Club
MED 246 / CMM 246 | Every Fall, Winter, Spring Quarter | Time: 12:00 - 1:00 pm
Day: Friday
First Day Spring Quarter: Friday, April 3, 2026
Location: Israni Biomedical Research Facility, Room 4103
Course Director: Amanda Lewis
Co-Instructors: Jeffrey D. Esko, Pascal Gagneux, Kamil Godula, Lars Bode
Course TAs: Dani Berman, Xin Du
Units: 1
Symbol Nomenclature for Glycans (SNFG):
https://www.ncbi.nlm.nih.gov/glycans/snfg.html
Harrison's Principles of Internal Medicine:
https://accessmedicine.mhmedical.com/book.aspx?bookid=3095
Current Literature in Glycobiology is a one-credit (per quarter) elective that provides a forum for informally discussing current papers in glycobiology research. Topics include glycan chemistry, biochemistry, genetics, cell biology, and molecular biology in animals, plants and microbes, as well as medical aspects of glycobiology.
| DATE |
PAPER |
PRESENTER |
FALL QUARTER 2025
|
| 9/26/25 |
Course introduction Paper Selection
|
Course TAs: Dani Berman, PhD student, A. Lewis Lab
Xin Du, Postdoctoral Fellow, Pediatrics
|
| 10/3/25 |
Basic Glycobiology Introduction |
Dani Berman, PhD student, A. Lewis Lab
Xin Du, Postdoctoral Fellow, Pediatrics |
| 10/10/25 |
CLASS CANCELED |
|
| 10/17/25 |
Identification and characterisation of vaginal bacteria-glycan interactions implicated in reproductive tract health and pregnancy outcomes |
Dani Berman, PhD student, A. Lewis Lab
|
| 10/24/25 |
Glycobiology and Virology Lecture |
Professor Scott Biering
|
| 10/31/25 |
RNA N-glycosylation enables immune evasion and homeostatic efferocytosis |
Christy Armstrong, SRA, A. Lewis Lab
|
| 11/7/25 |
Milk and mucin glycans orchestrate a synthetic infant gut microbiota structure |
Sarah Wax, PhD student, Godula Lab
|
| 11/14/25 |
Power Calculations Lecture |
Prof. Warren Lewis
|
| 11/21/25 |
Angstrom-resolution imaging of cell-surface glycans |
Paulo Olivieri, Postodc, Esko Lab
|
| 11/28/25 |
NO CLASS - THANKSGIVING HOLIDAY |
| 12/5/25 |
Methods Lecture |
Prof. Sam Meyers
|
WINTER QUARTER 2026
|
| 1/9/26 |
Introduction / Paper Selection |
Dani Berman Xin Du |
| 1/16/26 |
Broad-spectrum synthetic carbohydrate receptors (SCRs) inhibit viral entry across multiple virus families |
Veena Ramalingam (W. Lewis Lab) |
| 1/23/26 |
CLASS CANCELED |
|
| 1/30/26 |
Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy |
Dani Berman (A. Lewis Lab) |
| 2/6/26 |
Interferon-stimulated gene GALNT2 restricts respiratory virus infections |
Jackie Gallardo Beltran (A. Lewis Lab) |
| 2/13/26 |
Galectin-3 facilitates helicobacter pylori-induced apoptosis independently of sensing lysosomal damage |
Jaesoo Jung (Esko Lab) |
| 2/20/26 |
ILC3s regulate the gut microbiota via host intestinal galactosylation to limit pathogen infection in mice |
Kamalu Park (Esko Lab) |
| 2/27/26 |
Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors |
Shijun Lin |
| 3/6/26 |
Tuning CAR-T cells by targeting cancer-associated glycan in pancreatic cancer |
Desmond Cabanilla |
| 3/13/26 |
Dysregulation of glycosaminoglycans during oocyte maturation in vitro: Implications for developmental potential |
Elan Ortiz (Esko Lab) |
| 3/20/26 |
NO CLASS - FINAL EXAMS |
| 3/27/26 |
NO CLASS - CESAR CHAVEZ HOLIDAY |
SPRING QUARTER 2026
|
| 4/3/26 |
Introduction / paper selection |
Dani Berman, course TA |
| 4/10/26 |
Xylosyltransferase Engineering to Manipulate Proteoglycans in Mammalian Cells |
Paulo Olivieri (Esko Lab) |
| 4/17/26 |
Structures-of-ALG3-9-12-reveal-the-assembly-logic-of-the-N-glycan-oligomannose-core.pdf |
Shijun Li |
| 4/24/26 |
Cross-feeding Interactions between Fusobacterium nucleatum and the Glycan Forager Segatella oris |
Elan Ortiz |
| 5/1/26 |
Stats lecture-walk through practical training |
Dr. Warren Lewis |
| 5/8/26 |
https://www.nature.com/articles/s41467-025-64523-7 |
Sharon Godavarthi |
| 5/15/26 |
Mannose Metabolic Pathway Senses Glucose Supply and Regulates Cell Fate Decisions |
Dylan Mulaney |
| 5/22/26 |
Interferon-epsilon, an estrogen-induced type I interferon, is uniquely exploited by Neisseria gonorrhoeae via effects on sialic acid metabolism |
Rebecca Kirby |
| 5/29/26 |
Modeling glycans with AlphaFold 3: capabilities, caveats, and limitations |
Charlotte Liu |
| 6/5/26 |
The Protease Cathepsin K can Debulk the Cancer Glycocalyx |
Monae Pinner |
Contact
Please contact Tracy with any questions:
Tracy Gilstrap
Education Program Specialist
(858) 882-1378
tgilstrap@health.ucsd.edu