Skip to main content
Glycobiology Research & Training Center GRTC
  1. Glycobiology Research & Training Center
  2. Education
  3. Current Courses
  4. Advances in Glycobiology

Advances in Glycobiology

MED 225/CHEM 237/CMM 225
Offered every two years, Next Offering Spring 2023, First Day April 4, 2023
Location: Biomedical Research Facility 2 building, Room 1102
Time: 10:00–11:30 a.m. Tuesday & Thursday
Co-Directors: Jeffrey Esko and Philip Gordts

Additional Instructors:
Prof. Hudson Freeze, Sanford Burnham Prebys
Prof. Carlos Hirschberg, Boston University
Prof. Markus Aebi, ETH Zurich
Prof. Gerald Hart, University of Georgia
Prof. James Paulson, Scripps Research
Prof. Richard Cummings, Harvard Medical School
Prof. Ron Schnaar, Johns Hopkins University

Units: 4
Grading is based on regular attendance and class participation.

Advanced elective for upper level undergraduates, graduate, and health sciences students who have taken Introduction to Glycoscience (Chem 142/242) and courses in cell biology or biochemistry. This course consists of discussions of classic papers leading to modern concepts in glycobiology, with the objective of exploring the structure, metabolism, and function of glycans in biological systems. Students should develop a sense of the history of the field, seminal discoveries, and how these discoveries led to changes in the way scientists think about glycans. Students will be divided up into teams and make 1-2 presentations in consultation with a faculty member.

This year the course will be divided up into 5 modules:

DATE TOPIC/MODULE INSTRUCTOR PAPERS
4/4/23 Introduction

LECTURE 1:
A Short History of Glycobiology 		Jeff Esko
Philip Gordts

Richard Cummings

A lifetime of adventures in glycobiology


The origins of glycobiology
4/6/23 No Class Meeting due to San Diego Glycobiology Symposium
4/11/23 MODULE 1:
Virus Host Interactions: Adaptation of influenza to human airway receptors		 Jim Paulson Influenza Virus Receptor Specificity
The genetic character of O-D change in influenza A
Receptor specificity in human, avian, and equine H2 and H3 influenza virus isolates
4/13/23 ​MODULE 1:
Virus Host Interactions: Adaptation of influenza to human airway receptors		 Jim Paulson
4/18/23 MODULE 1:
Virus Host Interactions: Adaptation of influenza to human airway receptors		 Jim Paulson
​4/20/23 MODULE 1:
Virus Host Interactions: Adaptation of influenza to human airway receptors		 Jim Paulson
​4/25/23 MODULE 2:
N-glycans and Protein Folding		 Markus Aebi
4/27/23 MODULE 2:
N-glycans and Protein Folding		 Markus Aebi
​5/2/23 MODULE 2:
N-glycans and Protein Folding		 Markus Aebi
​5/4/23 MODULE 2:
N-glycans and Protein Folding		 Markus Aebi
​5/9/23 ​ MODULE 3:
Discovery of O-GlcNAc		 ​Jerry Hart
​5/11/23 ​ MODULE 3:
Discovery of O-GlcNAc		 ​Jerry Hart
​5/16/23 MODULE 3:
Discovery of O-GlcNAc		 ​Jerry Hart
​5/18/23 ​ MODULE 3:
Discovery of O-GlcNAc		 ​Jerry Hart
​5/23/23 MODULE 4:
Nucleotide Sugar Metabolism		 ​Carlos Hirschberg
​5/25/23 MODULE 4:
Nucleotide Sugar Metabolism		 ​Carlos Hirschberg
​5/30/23 MODULE 4:
Nucleotide Sugar Metabolism		 ​​Hud Freeze
6/1/23 MODULE 4:
Nucleotide Sugar Metabolism		 ​​Hud Freeze
​​6/6/23 LECTURE 2:
History of lectins		 Ron Schnaar
6/8/23 LECTURE 3:
Introduction to Bertozzi Nobel Prize / Watch Video
Bertozzi Nobel Prize		 Jeff Esko
Philip Gordts

Contact

If you are off campus and would like access to course materials, contact Tracy:

Tracy Gilstrap
Education Program Specialist
(858) 882-1378
tgilstrap@health.ucsd.edu