The goal of the Programs of Excellence in Glycosciences (PEG) is to translate emerging discoveries into new diagnostics and clinical applications, to build research capacity including technological resources, and a cadre of "scientifically bilingual" investigators fluent in glycan chemistry and biology that will sustain and advance the application of glycosciences to heart, lung, and blood research.

National Administrative Center

UC San Diego was selected as the National Administrative Center (PEGNAC) by the National Heart, Lung and Blood Institute (NHLBI), serving as the coordinator of six Programs of Excellence in Glycosciences' across the nation. The Center performs a range of functions including organizing investigator meetings, conference calls, External Review Panel meetings, arranging and designing and maintaining a website to support the PEGs.

For detailed information about the entire PEG Program please visit the National Administrative Center site.

UCSD PEG Program

In 2011 the National Heart, Lung and Blood Institute (NHLBI) recognized GRTC investigators at UC San Diego as one of the six PEG programs. This multidisciplinary partnership brings experts and new investigators together to focus on glycans and glycan-binding proteins in innate immunity, revealing many important functions in health and disease.

Our program consists of four innovative glycoscience research projects and five state-of-the-art core facilities.

Visit the UCSD PEG Program site for more details.

Projects
Siglec Modulation of Inflammatory Responses (PI: A.Varki)
Microbial Glycan Mimicry and Glycosides in Inflammatory Responses (PI: V. Nizet)
Genetic Analysis of Glycosaminoglycans in Inflammatory Responses (PI: J. Esko)
Hyaluronan Catabolism in Inflammatory Responses (PI: R. Gallo)
 
Cores
Glycosciences Skills Development (Director: J. Esko)
Shared Resources Core: Glycan Analysis & Synthesis (Director: B. Choudhury, Co-Investigator: G.-J. Boons)
Administrative and Mouse Management (Director: A. Varki)
Histopathology (Director: N. Varki)
Hematology and Clinical Chemistry (Director: D. Le)