Current literature in glycobiology 2015/2016

(MED 246 | BIOM 246 | CMM 246)
FA15, WI16, SP16
Fridays from 12:00pm - 1:00pm
BRF2, Room 4103

Previous Years: 2016-2017, 2015-2016, 2014-2015, 2013-2014, 2012-2013, 2011-2012, 2010-2011, 2009-2010
Back to Current Year

Publications are presented in an informal discussion setting to students, post-docs and faculty. Typically, there are 20-25 weekly attendees. Links to PubMed for each article are provided below. Topics include glycan chemistry, biochemistry, genetics, cell biology and molecular biology in animals, plants and microbes as well as medical aspects of glycobiology.

Faculty Instructors: Lars Bode, Jeffrey Esko, Ajit Varki, & Pascal Gagneux

Friday Publication Presented By Full Text
Oct 2 Course Welcome / Orientation
Lars Bode
Associate Professor

Guidelines (pdf)
Speaker Feedback (word)

Oct 9 The galectin-1-glycan axis controls sperm fertilizing capacity by regulating sperm motility and membrane hyperpolarization Eillen Tecle, Postdoctoral Researcher Article (pdf)
Oct 16 CARTA Symposium CARTA Symposium  
Oct 23 Targeting Human Cancer by a Glycosaminoglycan Binding Malaria Protein Daniel Sandoval Article (pdf)
Oct 30 Modifications of carbohydrate residues in the sheep oviductal ampulla after superovulation Hector Sequoyah Reynoso Article (pdf)
Nov 6 Glycosyltransferase ST6GAL1 contributes to the regulation of pluripotency in human pluripotent stem cells Greg Trieger Article (pdf)
Nov 13 Notum deacylates Wnt proteins to suppress signalling activity Austen Michalak Article (pdf)
Nov 20 An intrinsic mechanism of secreted protein aging and turnover Alex Hamil Article (pdf)
Nov 27 no class Thanksgiving Holiday
Dec 4 Society for Glycobiology Annual Meeting Society for Glycobiology Meeting  
Dec 11 Structure and mechanism of an active lipid-linked oligosaccharide flippase Oluwatunmise Olayinka Article (pdf)
Dec 18 Targeting Siglecs with a sialic acid-decorated nanoparticule abrogates inflammation Shoib Siddiqui Article (pdf)
Dec 25 no class Winter Break
Jan 1, 2016 no class Winter Break
Jan 8 PTP functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is esential for excitatory synaptic transmission Chelsea Painter Article (pdf)
Jan 15 Analysis of site-specific N-glycan remodeling in the endoplasmic reticulum and the Golgi Mike Vaill Article (pdf)
Jan 22 Cellobionic acid utilitzation: from Neurospora crassa to Saccharomyces cerevisiae Chris Fisher Article (pdf)
Jan 29 Structural basis of Lewis antigen binding by the Helicobacter pylori adhesin BabA Nazneen Khan Article (pdf)
Feb 5 Glypican-1 identifies cancer exosomes and detects early pancreatic cancer Ferdous Anower-E-Khuda Article (pdf)
Feb 12 N-Glycosylation of cholera toxin B subunit in Nicotiana benthamiana: impacts on host stress response, production yield and vaccine potential Daniel Honigfort Article (pdf)
Feb 19 Therapeutic lymphangiogenesis ameliorates established acute lung allograft rejection Ying Lin Article (pdf)
Feb 26 Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition Alison Coady Article (link)
Mar 4 A single glycan on IgE is indispensable for initiation of anaphylaxis. Asami Yamamura Article (pdf)
Mar 11 Engineering a Therapeutic Letin by Uncoupling Mitogenicity from Antiviral Activity Bastian Ramms Article (pdf)
Mar 18 Two papers to introduce the concept of frequency dependent selection and apply the logic to siglec variants in natural populations. Stevan Springer Article 1 (pdf)
Article 2 (pdf)
Mar 25 San Diego Glycobiology Symposium San Diego Glycobiology Symposium
Apr 1 Hyaluronan synthesis is necessary for autoreactive T-cell trafficking, activation, and Th1 polarization Miriam Cohen Article (pdf)
Apr 8 Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosis Kelsey Krug Article (pdf)
Apr 15 Trichomonas vaginalis Lipophosphoglycan Exploits Binding to Galactin-1 and -3 to Modulate Epithelial Immunity Corinna Landig Article (pdf)
Apr 22 Inter-PEG Inter-PEG  
Apr 29 Targeting prion-like protein doppel selectively suppresses tumor angiogenesis Ryan Weiss Article (pdf)
May 6 An inhibitor of chondroitin sulfate proteoglycan synthesis promotes central nervous system remyelination Chrissa Dwyer Article (pdf)
May 13 The nutrient sensor OGT in PVN neurons regulates feeding Frederico da Silva Article (pdf)
Supplement (pdf)
May 20 Inhibition of adipogenesis in 3T3-L1 cells and suppression of abdominal fat accumulation in high-fat diet-feeding C57BL/6J mice after downregulation of hyaluronic acid Tatsuya Dokoshi Article (pdf)
May 27 Highly efficient delivery of functional cargoes by the synergistic effect of GAG binding motifs and cell-penetrating peptides Matthew Naticchia Article (pdf)
June 3 Direct visualization of specifically modified extracellular glycans in living animals Anne Phan Article (pdf)
Supplement (pdf)
Jun 10 O-GlcNAc modification blocks the aggregation and toxicity of the Parkinson's disease associated protein alpha-synuclein Jonathan Okerblom Article (pdf)
Jun 17 Defective Intestinal Mucin-Type O-Glycosylation Causes Spontaneous Colitis-Associated Cancer in Mice Sabrina Etzold Article (pdf)