Current literature in glycobiology 2014/2015

(MED 246 | BIOM 246 | CMM 246)
FA14, WI15, SP15
Fridays from 12:00pm - 1:00pm
BRF2, Room 4103

Previous Years: 2016-2017, 2015-2016, 2014-2015, 2013-2014, 2012-2013, 2011-2012, 2010-2011, 2009-2010
Back to Current Year

Publications are presented in an informal discussion setting to students, post-docs and faculty. Typcially, there are 20-25 weekly attendees. Links to PubMed for each article is provided below. Topics include glycan chemistry, biochemistry, genetics, cell biology and molecular biology in animals, plants and microbes as well as medical aspects of glycobiology. Registration for the course (1 credit per quarter) is done through the registrar's office.

Faculty Instructors: Drs. Lars Bode, Jeffrey Esko, Ajit Varki, & Pascal Gagneux

Friday Publication Presented By Full Text
Sept 19 Course Welcome
Lars Bode, Associate Professor
Guidelines Image of a pdf symbol
Sept 26 No Session
Oct 3 Paszek MJ, et al. (2014) The cancer glycocalyx mechanically primes integrin-mediated growth and survival. Nature. 511(7509):319-25 PMID: 25030168
Jonathan Okerblom, BMS
Article
Oct 10
CARTA Symposium
Oct 17 Goto Y, et al. (2014) Innate lymphoid cells regulate intestinal epithelial cell glycosylation. Science. 345(6202):1254009 PMID: 25214634
Daniel Sandoval, BMS
Article
Oct 24 Zhou RW, et al. (2014) N-glycosylation bidirectionally extends the boundaries of thymocyte positive selection by decoupling Lck from Ca2+ signaling . Nat Immunol. PMID: 25263124
Corinna Landig, Grad Student
Article Graphic of a pdf
Oct 31 Suez J, et al. (2014) Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature. PMID: 25231862
Pranitha Kamat, Postdoc
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Nov 7 Cavallari M, et al. (2014) A semisynthetic carbohydrate-lipid vaccine that protects against S. pneumoniae in mice. Nat Chem Biol. PMID: 25282505
Sequoyah Reynoso, BMS
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Nov 14 Rosenbaum EE, et al. (2014) Mutations in four glycosyl hydrolases reveal a highly coordinated pathway for rhodopsin biosynthesis and N-glycan trimming in Drosophila melanogaster. PLoS Genet. PMCID: PMC24785692
Flavio Schwarz, Postdoc
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Nov 21 Tagliabracci VS, et al (2014) Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proc Natl Acad Sci USA. PMCID: PMC3992636
Jerry Fong, Postdoc
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Nov 28
Thanksgiving Holiday
Dec 5 Liang et al (2014) Complex N-linked glycans serve as a determinant for exosome/microvesicle cargo recruitment. J Biol Chem. 2014 Nov 21;289(47):32526-37. PMID: 25261472
Chelsea Painter, BMS
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Dec 12 Stowell SR, et al (2014) Microbial glycan microarrays define key features of host-microbial interactions . Nat Chem Biol. 10(6):470-6. PMCID: PMC4158828
Sabrina Etzold, Postdoc
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Dec 19
Winter Break
Dec 26
Winter Break
Jan 2, 2015
Winter Break
Jan 9
San Diego Glycobiology Symposium
Jan 16 Julithe R, et al (2014) Modification of the Hepatitis B Virus Envelope Protein Glycosylation Pattern Interferes with Secretion of Viral Particles, Infectivity, and Susceptibility to Neutralizing Antibodies. J Virol. 88(16): 9049-59. PMCID: PMC4136284
Karthik Sreedhara, Postdoc
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Jan 23 Yilmaz B, et al (2014) Gut Microbiota Elicits a Protective Immune Response against Malaria Transmission. Cell. 159(6):1277-89. PMCID: PMC4261137
Anel Lizcano, Postdoc
ArticleGraphic of pdf
Jan 30 Akiyoshi S, et al (2015) RNAi screening of human glycogene orthologs in the nematode Caenorhabditis elegans and the construction of the C. elegans glycogene database . Glycobiology. 25(1):8-20. PMCID: PMC4245905
Eillen Tecle, Postdoc
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Feb 6 Cuskin F, et al (2015) Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature. 517(7533): 165-9. PMID: 25567280
Irene Lew, Undergrad
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Feb 13 Kondoh D, et al (2014) Molecular Clock Regulates Daily 1–2-Fucosylation of the Neural Cell Adhesion Molecule (NCAM) within Mouse Secondary Olfactory Neurons. J Bio Chem. 289 (52):36158-65. PMCID: PMC4276879
Yuko Matsui, Postdoc
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Feb 20
CARTA Symposium
Feb 27 Takumi K, et al (2014) Endogenous airway mucins carry glycans that bind Siglec-Fand induce eosinophil apoptosis. J Allergy Clin Immunol. S0091-6749(14)01522-X. PMID: 25497369
Chloe Autran, Grad Student
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Mar 6 Martinez-Martin N, et al (2015) Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization. Nat Commun. 6:6163 do: 10.1038/ncomms7163. PMID: 25625471
Miriam Cohen, Research Scientist
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Mar 13 Patel VN, et al (2014) Hs3st3-modified heparan sulfate controls KIT+ progenitor expansion by regulating 3-O-sulfotransferases. Dev Cell. 29(6):662-73. PMCID: PMC4105206
Anne Phan, Undergrad
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Mar 20 Petit D, et al (2014) Integrative View of 2,3-Sialyltransferases (ST3Gal) Molecular and Functional Evolution in Deuterostomes: Significance of Lineage-Specific Losses. Mol Biol Evol. Epub. PMID: 25534026
Stevan Springer, Postdoc
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Mar 27
Cesar E. Chavez Holiday
Apr 3 Lan BT et al (2015) Modulation of the proteoglycan receptor PTPσ promotes recovery after spinal cord injury. Nature. 518(7539):404-8. PMCID: PMC43326236
Chrissa Dwyer, Postdoc
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Apr 10 Pan Y, et al (2014) Podoplanin requires sialylated O-glycans for stable expression on lymphatic endothelial cells and for interaction with platelets. Blood. 124(24):3656-65. PMCID: PMC4256915
Lingquan Deng, Postdoc
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Apr 17 Shewell LK et al (2014) The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity. Proc Natl Acad Sci USA. 111(49):E5312-20. PMC4267402
Frederico Da Silva, Postdoc
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Apr 24 Li X, et al (2015) Expanding xylose metabolism in yeast for plant cell wall conversion to biofuels. Elife. 3;4 PMCID: PMC4338637
Chris Fisher, Graduate Student
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May 1 Taylor P, et al (2014) Fringe-mediated extension of O-linked fucose in the ligand-binding region of Notch1 increases binding to mammalian Notch ligands. Proc Natl Acad Sci USA. 111(20):7290-5. PMCID: PMC4034240
Ajit Varki, Professor
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May 8 Zhu Y, et al (2015) O-GlcNAc occurs cotranslationally to stabilize nascent polypeptide chains. Nat Chem Biol. 11(5):319-25. PMID: 25774941
Wenyong Tong, Postdoc
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May 15
CARTA Symposium
May 22
Mike Jennings Seminar
May 29
Michael Williams, BMS
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Jun 5
Josh Chan, BMS
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