Current literature in glycobiology 2012/2013

(MED 246 | BIOM 246 | CMM 246)
FA12, WI13, SP13
Fridays from 12:00pm - 1:00pm
CMM-East, Room 1079 (1st Floor Conference Room)

Previous Years: 2016-2017, 2015-2016, 2014-2015, 2013-2014, 2012-2013, 2011-2012, 2010-2011, 2009-2010
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Publications are presented in an informal discussion setting to students, post-docs and faculty. Typcially, there are 20-25 weekly attendees. Links to PubMed for each article is provided below. Topics include glycan chemistry, biochemistry, genetics, cell biology and molecular biology in animals, plants and microbes as well as medical aspects of glycobiology. Registration for the course (1 credit per quarter) is done through the registrar's office.

Faculty Instructors: Drs. Lars Bode, Jeffrey Esko, & Pascal Gagneux

Friday Publication Presented By Full Text
Sept 14 Course Welcome
Lars Bode, Assistant Professor
Guidelines & Intro Image of a pdf symbol
Sept 21 Schjoldager, KT. et al (2012) Probing isoform-specific functions of polypeptide GalNAc-transferases using zinc finger nuclease glycoengineered SimpleCells. Proc Natl Acad Sci U S A. 109(25):9893-8. PMC3382506
Jeff Esko, Professor
Supplemental Image of a pdf symbol
Sept 28 Yi W, et al (2012) Phosphofructokinase 1 glycosylation regulates cell growth and metabolism. Science. 337 (6097):975-80. PMID: 22923583
Bryan Thacker, Predoctoral Fellow
Supplemental Image of a pdf symbol
Oct 5 Wang Y, et al (2012) Platelet biogenesis and functions require correct protein O-glycosylation. Proc Natl Acad Sci USA. PMID: 22988088
Philip Gordts, Postdoctoral Fellow
Oct 12 Brown S, et al (2012) Methicillin resistance in Staphyloccus aureus requires glycosylated wall teichoic acids. Proc Natl Acad Sci USA. PMID: 23027967
Leela Davies, Predoctoral Fellow
Oct 19 Hirose, Y et al (2012) Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis. Proc Natl Acad Sci U S A. 109(11):4263-8. PMID: 22371575
Jon Gonzales, Predoctoral Fellow
Oct 26 Bowden, TA et al (2012) Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped during Glycan Biosynthesis. JACS. Epub. PMID: 23025485
Oliver Pearce, Postdoctoral Fellow
Nov 2 May JF, et al (2009) A tethering mechanism for length control in a progressive carbohydrate polymerization. Proc Natl Acad Sci USA 106(29). PMCID: PMC2715488
Stevan Springer, Postdoctoral Fellow
Nov 9 Takanaka H, et al (2012) A Simple Synthesis of Sugar Nucleoside Diphosphates by Chemical Coupling in Water. Angew Chem Int Ed Engl. Epub. PMID: 23065967
Corinna Landig,
Visiting Graduate Student
Nov 16 Nicolaou N, et al (2012) Gain of Glycosylation in integrin a3 causes lung disease and nephrotic syndrome. J Clin Invest. pii: 64100. PMID: 23114595
Flavio Schwarz, Postdoctoral Fellow
Nov 23
Thanksgiving Holiday
Nov 30 Oda M, et al (2012) Clostridium perfringens Alpha-toxin Recognizes the GM1a-TrkA Complex. J Biol Chem. 287(39):33070-9. PMCID: PMC3463319
Anne Bergfeld, Postdoctoral Fellow
Dec 7 Hehemann JH, et al (2012) Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes. Proc Natl Acad Sci USA. 109(48):19786-91. PMID: 23150581
Jerry Fong, Postdoctoral Fellow
Dec 14 Wang P, et al (2012) O-GlcNAc cycling mutants modulate proteotoxicity in Caenorhabditis elegans models of human neurodegenerative diseases. Proc Natl Acad Sci USA. 109(43):17669-74. PMID: 22988095. PMCID: PMC3491483
Emylie Seamen, Postdoctoral Fellow
Dec 21
Winter Break
Dec 28
Winter Break
Jan 4, 2013
Winter Break
Jan 11
San Diego Glycobiology Symposium
Jan 18 Boscher C, et al (2012) Galactin-3 protein regulates mobility of N-cadherin and GM1 ganglioside at cell-cell junctions of mammary carcinoma cells. J Biol Chem. 287(39):32940-52. PMCID: PMC3463368
Jonathan Okerblom,
Predoctoral Fellow
Article pdf
Jan 25 Pacheco AR, et al (2012) Fucose sensing regulates bacterial intestinal colonization. Nature. 492(7427):113-7. PMCID: PMC3518558
Xander van Wijk, Postdoctoral Fellow
Article grapic of pdf
Feb 1 Fujikawa T, et al (2012) Surface a-1,3-Glucan Facilitates Fungal Stealth Infection by Interfering with Innate Immunity in Plants. PLoS Pathog. 8(8):e1002882. PMCID: PMC3426526
Pascal Gagneux, Assistant Professor
Article Pdf Symbol
Feb 8 Klaas M, et al (2012) Sialoahesin Promotes Rapid Proinflammatory and Type I IFN Responses to a Sialylated Pathogen, Campylobacter jejuni. J Immunol. 189(5):2414-22. PMCID: PMC3442253
Masaya Yamaguchi,
Postdoctoral Fellow
Article grapic of a pdf
Feb 15 Shah A, et al (2013) A loss of hippocampal perineuronal nets produces deficits in dopamine system function: relevance to the positive symptoms of schizophrenia. Transl Psychiatry. 3:e215. PMCID: PMC3566725
Annie Samraj, Postdoctoral Fellow
Article grapic of the pdf symbol
Feb 22 Chen W, et al (2013) Induction of Siglec-G by RNA Viruses Inhibits the Innate Immune Response by Promoting RIG-I Degradation. Cell. 152(3):467-78. PMID: 23374343
Wenyong Tong, Postdoctoral Fellow
Article graphic of pdf symbol
Mar 1 Antoniak S, et al (2013) PAR-1 contributes to the innate immune response during viral infection. J Clin Invest. pii: 66125. PMID: 23391721
Jun Muto, Postdoctoral Fellow
Article graphic of pdf image
Mar 8 Ramhorst R, et al (2012) Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss. Glycobiology. 22(10):1374-86. PMID: 22752006
Chloe Autran, Predoctoral Student
Article graphic of an pdf file
Mar 15 Kidder D, et al (2013) Sialoadhesin Ligand Expression Identifies a Subset of CD4+Foxp3- T Cells with a Distinct Activation and Glycosylation Profile. J Immunol. 190(6):2593-602. PMCID: PMC3586974
Evelyn Jantscher-Krenn,
Postdoctoral Fellow
Article graphic of pdf image
Mar 22 Moore PL, et al (2012) Evolution of an HIV glycan–dependent broadly neutralizing antibody epitope through immune escape. Nat Med. 18(11):1688-92. PMCID: PMC3494733
Lingquan Deng, Postdoctoral Fellow
Article graphic representing a pdf file
Supplement graphic of pdf file type
Mar 29
Cesar Chavez Holiday
Apr 5 Howerton CL, et al (2013) O-GlcNAc transferase (OGT) as a placental biomarker of maternal stress and reprogramming of CNS gene transcription in development. Proc Natl Acad Sci USA. 110(13):5169-74. PMID: 23487789
Yuko Matsui, Visting Professor
Article graphic of a pdf symbol
Apr 12
Apr 19 Yu ZT, et al The principal fucosylated oligosaccharides of human milk exhibit prebiotic properties on cultured infant microbiota. (2013) Glycobiology. 23(2):169-77. PMCID: PMC3531294
Spencer Moore, Predoctoral Student
Article graphic symbol of a pdf icon
Apr 26 Hoogeboom R, et al. A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi. (2013) J Exp Med. 210(1):59-70. PMCID: PMC3549718
Heinz Laubli, Postdoctoral Fellow
Article graphic of a pdf file